Orion

The constellation Orion based on Orion, the Hunter appears in a fantasy sequence in the Muppet Babies episode "Where No Muppet has Gone Before." While traveling through space the babies seek him out for instruction on how to return to the nursery before Nanny realizes they're not sleeping.

Later in the episode, Baby Bunsen and Baby Beaker, point out "Orion's Belt," a collection of three stars, Alnitak, Alnilam and Mintaka evenly spaced in a line.