Dr. Teeth and the Electric Mayhem are the house band on The Muppet Show. They mostly stick to rock music, but they're capable of playing other styles, including jazz and (unwillingly) classical. Although Dr. Teeth is the leader, he is not the only one to provide lead vocals. Floyd Pepper is often a lead singer on songs, and Janice is lead singer on a handful of songs.
They drive around in a brightly-painted bus with psychedelic swirls and colors.
Music was always an important part of Jim Henson's work. He had a strong interest in all types and had an eclectic record library. When he began writing proposals and creating concepts for The Muppet Show in the late 1960s, they always included a house band that was to appear in each episode. At that time, Jim had a strong interest in the counter-culture movement (as evidenced by his experimental film Youth 68) and sought to reflect that in the composition of the band. One proposal from about 1970 says that the band would, "...do songs like "Sunshine" from Hair. In fact, they are all dressed to out-hair the Hair cast." The Electric Mayhem as we know it first appeared in 1975 on the Muppet Show pilot Sex and Violence. A page of ideas for the show written by Jim describes the band this way: "Rock act - far-out, elaborate weird equipment, big amps...".
- Dr. Teeth on keyboards, pianos, and vocals.
- Floyd Pepper on bass guitar and vocals (occasionally cello, banjo, and vibes).
- Zoot on saxophone (occasionally clarinet, flute, and tuba).
- Janice on lead guitar and vocals (occasionally tambourine, trombone, and trumpet).
- Animal on drums.
- Lips on trumpet (The Muppet Show Season 5, 1980; The Great Muppet Caper, 1981; A Muppet Family Christmas, 1987; The Muppets at Walt Disney World, 1990; The Muppet Christmas Carol, 1992; Christmas in Rockefeller Center, 2009; "Jungle Boogie", The Muppets, and "Kodachrome", 2015; Outside Lands Music and Arts Festival, 2016; The Muppets Take the Bowl, 2017; The Muppets Take the O2, 2018; Muppets Haunted Mansion and Dear Earth, 2021)
- A Bongo Player (episode 413)
- A brass section consisting of a clarinet player and two trumpet players (one of whom was Bobby Benson) (season 2 of The Muppet Show)
- Clifford on percussion (The Muppets at Walt Disney World, 1990)
- Don Knotts on stand up bass (episode 201)
- Jim on banjo (The Muppet Show: Sex and Violence pilot)
- Rizzo the Rat on cymbals (episode 511)
- Rowlf on piano (episode 121 (German version only)), (episode 424, episode 513), in addition to Dr. Teeth (The Muppet Christmas Carol)
- Scooter on percussion (The Muppet Movie)
- Three frog backup singers (episode 406)
- Trombone player (episode 517)
- Trumpet Girl on trumpet (episode 123 of The Muppet Show) and trombone (episode 505, episode 513)
- Zeke on banjo (episode 424) and marimba (episode 523)
- A drummer (Episode 505)
- Beaker on vocals (episode 424, Studio DC Hosted by Selena Gomez)
- Ninja Rogers on drums (The Treasure of Peg-Leg Wilson)
- Hal Linden on clarinet ( Episode 517: Hal Linden )