Her favorite food is pizza, and she loves playing monster ball (which is kind of like soccer, but for monsters). She is shown to be in the care of two foster parents, Dalia and Clem. She is also good friends with Elmo.
Karli starred in another series of videos that debuted on the site in October 2019, focusing on substance abuse. It is explained that Karli's mother is away getting treatment for her addiction, which was only implied in the earlier foster care videos. Karli also appeared in a musical outreach video for their "Violence" initiative.
- The National "Meet Karli: The Newest Neighbor on Sesame Street"