Sansone started in television at age eleven doing reporting for Good Morning America and The Tonight Show. She also co-hosted Live with Regis and Kelly with Regis Philbin while Kelly Ripa was on maternity leave. Sansone co-anchored Good Day LA on KTTV FOX 11 in Los Angeles and was a field reporter for WNBC 4 New York, appearing daily on LX New York. She has also appeared on shows and networks such as Access Hollywood, Extra, On the Red Carpet, ABC, NBC, MTV, TV Guide Network, CBS Sports, and ESPN.
Kermit the Frog appeared with Sansone on The 9 in December 2006. In between helping promote Before You Leap and A Green and Red Christmas Sansone flirted with the fame frog and appeared quite star-stuck in presence of the famed amphibian, a point she reiterated on her official website:
“I think I'm in love!
OMG! I just met Kermit The Frog.... I have the best job ever!! I can't believe it! He was my very special guest host on The 9 today! I've met a lot of famous people and I've never been so star struck as I was today. I couldn't stop blushing! He was AWESOME! The cutest lil' frog I've ever met! BTW...I think he liked me :) Watch out Piggy!
I feel like our little web show is becoming everything we ever dreamed it would be. I mean it doesn't get much bigger than Kermit T. Frog. The whole 9 gang is still in awe! What a day! Be sure to see the photos of me and Kermie in the gallery.”
According to the August 4, 2006 episode of The 9, Muppet Wiki is Sansone's "favorite new website".