Sally's show allows Grouches to vent their problems (and get hissed at by the equally grouchy audience). Needless to say, she's not very helpful in comforting her guests (she is a Grouch after all).
Oscar the Grouch is her most frequent guest. Among his reasons for being on the show are taking care of a lost kitten in Episode 3120 and falling in love with Grundgetta in Episode 3519. Other guests include Baby Bear and Goldilocks in episode 3486.