St. Elsewhere is a medical drama that aired on NBC from 1982 to 1988. The series follows doctors at a Boston teaching hospital called St. Eligius. The series included a wide variety of cross-overs and in joke references to other TV shows (from The Bob Newhart Show to Cheers).
- In the third season episode "Red, White, Black and Blue" (1985), child patient Sean Wilkes plays with a plush Ernie doll before falling off of a chair.
- In the fourth season episode "The Boom Boom Womb" (1986), after Dr. Elliot Axelrod accidentally kills a co-worker's pet pigeon, he "had this nightmare that I killed Big Bird. This angry lynch mob of kids was chasing me down Sesame Street."
- Alan Arkin played Jerry Singleton (3 episodes, 1983)
- G. W. Bailey played Dr. Hugh Beale (1982-1983)
- James Coco played Arnie in "Cora and Arnie" (1982)
- Jack Dodson played Judge Farnham (1984-1988)
- Conchata Ferrell played Gina Barnett in "Hearts" (1983)
- Bruce Greenwood played Dr. Seth Griffin (1985-1988)
- Helen Hunt played Clancy Williams (1984-1986)
- Howie Mandel played Dr. Wayne Fiscus
- Jeff McCracken played Mr. Stritch in "Up and Down" (1986)
- Laraine Newman played Jane "Tweety" Zontell in three episodes (1982)
- Laurie O'Brien played Mrs. Morgen in "Working" (1983)
- Austin Pendleton played Mr. Entertainment in "Under Pressure" (1983) and "Vanity" (1984)
- Rhea Perlman played Carla Tortelli in "Cheers" (1985)
- Michael Richards played Bill Wolf (5 episodes, 1984-1985)
- Doris Roberts played Cora in "Cora and Arnie" (1982)
- Denzel Washington played Dr. Philip Chandler
- George Wendt played Norm Peterson in "Cheers" (1985)
- Alfre Woodard played Dr. Roxanne Turner (1985-1988)